Blastocyst culture is the process of growing the embryo in the laboratory for two or more days until they are referred to as a blastocyst embryo. The frozen blastocyst transfer is done on the fifth day, and it is the final stage of embryo development before it comes out of the egg by breaking the Zona Pellucida and then plants itself in the uterine wall.
Until recently, it was challenging to culture embryos to the blastocyst stage. As a result of scientific advancements, culture mediums have been created that imitate the changing conditions of the reproductive system and are tailored to the specific needs of the embryo as it passes through the fallopian tubes. In a laboratory setting, 65% of embryos successfully develop to the blastocyst stage. The blastocysts contain two different cells types –
Usually, blastocyst culture is recommended in various situations –
An embryo's appearance cannot dependably foretell implanted blastocyst development or implantation potential. It may be challenging to decide which embryos have the best chance of developing into a healthy pregnancy early in the embryonic process. By holding the embryos in the lab until day 5, when they start to develop into blastocysts, any variations between them can become more obvious. Hence, when there are a variety of embryos to choose from, blastocyst culture enables the embryology team to choose the best embryos for transfer.
Up to 60% of each blastocyst has the potential to implant. A healthy singleton pregnancy is more likely to happen with the transfer of a single blastocyst with a high implantation rate. Remember that multiple blastocyst implantation might cause multiple births.
The potential risk of blastocyst transfer is the possibility that some embryos won't make it through five days of culture outside the human body. As a result, there will be fewer embryos overall that are accessible for freezing and transfer. After day 3, the embryos cease maturing, and therapy ends without the possibility of an IVF embryo transfer for a tiny percentage of couples (5%). This condition is referred to as embryonic block and may be the root cause of infertility.
A blastocyst transfer follows a similar procedure to an In Vitro Fertilization (IVF). The age of the embryo during implantation is the sole difference between a blastocyst transfer and a standard IVF cycle procedure. An embryo is roughly four days old, but a blastocyst transfer requires an embryo to be six days old. The following steps are involved in the blastocyst transfer –
Multiple births or any other medical complications during blastocyst transfer are less likely to happen because of cutting-edge technology used by highly experienced fertility experts at Indira IVF. At Indira IVF, skilled embryologists use blastocyst transfer to treat infertility in women and lower the risk of multiple pregnancies.
Visit your nearest Indira IVF centre to know more about Blastocyst Culture & Embryo Transfer from our Fertility Experts.
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